Expert Video - What causes MDS?

MDS expert, Dr Stephen Nimer, explains that with a few exceptions, the exact causes of myelodysplastic syndromes (MDS) are unknown. Some factors may increase the risk of developing MDS, including: certain genetic changes, previous chemotherapy, exposure to high dose radiation, and long-term exposure to certain chemicals. MDS happens when something affects the bone marrow cells, changing the DNA’s instructions for making blood cells, but doctors don’t know exactly what affects the cells to cause MDS in a particular person at a particular time.

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This educational activity has been developed by the Myelodysplastic Syndromes Foundation, Inc. and Mechanisms in Medicine Inc.

This activity is supported by an educational grant from Acceleron Pharma, Celgene Corporation, Jazz Pharmaceuticals, Novartis, and Takeda Oncology.

This website is part of the Animated Patient™ series developed by Mechanisms in Medicine Inc., to provide highly visual formats of learning for patients to improve their understanding, make informed decisions, and partner with their healthcare professionals for optimal outcomes.